Vitamin D Analogs in Cancer Prevention and TherapyJ. Reichrath, M. Friedrich, W. Tilgen Springer Science & Business Media, 23 มิ.ย. 2003 - 432 หน้า This volume provides a comprehensive, highly readable overview of the topics discussed at the First International Symposium on "Vitamin D Analogs in Cancer Prevention and Therapy" held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer. |
เนื้อหา
Evolution and Function of Vitamin D | 3 |
Current Understanding of the Function of the Nuclear Vitamin D Receptor in Response to Its Natural and Synthetic Ligands | 29 |
Approaches to Evaluating the Association of Vitamin D Receptor Gene Polymorphisms with Breast Cancer Risk | 43 |
Ligand StructureFunction Relationships in the Vitamin D Endocrine System from the Perspective of Drug Development Including Cancer Treatment | 55 |
Antiproliferative Signalling by 125OH₂D₃ in Prostate and Breast Cancer Is Suppressed by a Mechanism Involving Histone Deacetylation | 83 |
Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D Compounds in Breast Cancer Cells | 99 |
Why? | 111 |
A Novel Vitamin DRegulated ImmediateEarly Gene IEX1 Alters Cellular Growth and Apoptosis | 123 |
The Vitamin D ReceptorButyrate Connection | 247 |
Analysis of the Vitamin D system in Cutaneous Malignancies | 259 |
Antitumor Effects of Vitamin D Analogs | 271 |
Evaluation of Vitamin D Analogs as Therapeutic Agents for Prostate Cancer | 273 |
Design Synthesis and Biological Studies of the ARingModified 125Dihydroxyvitamin D3 Analogs | 289 |
Induction of Apoptosis by Vitamin D Metabolites and Analogs in a Glioma Cell Line | 319 |
Vitamin D Analogs and Breast Cancer | 333 |
A LowCalcemic Vitamin D Analog Ro 254020 Inhibits the Growth of LNCaP Human Prostate Cancer Cells with Increased Potency by Producing an ... | 349 |
The Particular Role of the Skin | 135 |
Cultured Rat Growth Plate Chondrocytes Express Low Levels of 1𝛼Hydroxylase | 147 |
in Glioblastoma Multiforme A Possible Role in Tumor Progression? | 151 |
Regulation of the 25Hydroxyvitamin D1𝛼Hydroxylase Gene and Its Splice Variant | 157 |
Combination of Vitamin D Metabolites with Selective Inhibitors of Vitamin D Metabolism | 169 |
Importance Of Cytochrome P450Mediated Metabolism in the Mechanism of Action of Vitamin D Analogs | 189 |
The Vitamin D System in Cancer | 203 |
The Role of Vitamin D in Prostate Cancer | 205 |
Vitamin D Autocrine System and Prostate Cancer | 223 |
Analysis of the Vitamin D System in Cervical Carcinomas Breast Cancer and Ovarian Cancer | 239 |
Prospects for Vitamin D receptor Modulators as Candidate Drugs for Cancer and Autoimmune Diseases | 353 |
The Role of Reactive Oxygen Species in the Anticancer Activity of Vitamin D | 357 |
Vitamin D in Cancer Prevention | 369 |
Ecologic Studies of Solar UVB Radiation and Cancer Mortality Rates | 371 |
Phytoestrogens and 17𝛽Estradiol Influence Vitamin D Metabolism and Receptor ExpressionRelevance for Colon Cancer Prevention | 379 |
Efficacy and Mechanism of Action of 1𝛼hydroxy24ethylCholecakiferol 1𝛼OHD5 in Breast Cancer Prevention and Therapy | 393 |
Regulation of Extrarenal Vitamin D Metabolism as a Tool for Colon and Prostate Cancer Prevention | 413 |
Modulation of XrayInduced Apoptosis in Human Keratinocytes HaCaT by 125Dihydroxyvitamin D₃ | 427 |
ฉบับอื่นๆ - ดูทั้งหมด
Vitamin D Analogs in Cancer Prevention and Therapy J. Reichrath,M. Friedrich,W. Tilgen ชมบางส่วนของหนังสือ - 2013 |
Vitamin D Analogs in Cancer Prevention and Therapy J. Reichrath,M. Friedrich,W. Tilgen ไม่มีตัวอย่าง - 2012 |
Vitamin D Analogs in Cancer Prevention and Therapy J. Reichrath,M. Friedrich,W. Tilgen ไม่มีตัวอย่าง - 2012 |
คำและวลีที่พบบ่อย
1,25-dihydroxyvitamin D3 24-hydroxylase 25-hydroxyvitamin A-ring acid anticancer antiproliferative apoptosis assay Binderup binding Biochem biological activity breast cancer breast cancer cells butyrate Caco-2 cells calcemic calcitriol calcium cancer cell lines Cancer Res carcinoma Carlberg cell cycle cell growth cellular Chen colon cancer cytochrome P450 D3 analogs differentiation effects Endocrinol Endocrinology enzyme expression extrarenal Feldman gene genistein growth inhibition Holick MF hormone human keratinocytes human prostate hypercalcemia increased incubation induced inhibitors interaction keratinocytes kidney kinase Koeffler HP la-OHase levels liarozole ligand LNCaP cells Mehta metabolism metabolites molecular mRNA normal Norman AW nuclear nuclear receptor pathway polymorphisms potent proliferation prostate cancer prostate cancer cells prostate cells protein psoriasis radiation rats regulation serum side chain skin steroid studies synthesis tion tissue transcription transfected treatment tumor Uskokovic VDRE VDRnuc vitamin D analogs vitamin D compounds vitamin D metabolites vitamin D receptor vitamin D3 vitro vivo
บทความที่เป็นที่นิยม
หน้า 425 - KUIPER GG, LEMMEN JG, CARLSSON B, CORTON JC, SAFE SH, VAN DER SAAG PT, VAN DER BURG B and GUSTAFSSON JA (1998), 'Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta'.