Sun Protection in Man

ปกหน้า
Elsevier, 31 ก.ค. 2001 - 780 หน้า
"Sun Protection in Man" looks at the beneficial and harmful effects of solar radiation. The physiological consequences of sun exposure have been systematically studied starting at the end of the nineteenth century and we now have accumulated knowledge about how Caucasian and Asian skins reacts to solar radiation. The chemical effects of solar ultraviolet radiation have been analyzed with particular emphasis during the second half of the twentieth century. Research on micro-organisms has allowed us to understand the mechanisms of UV-induced mutagenesis and photosensitization. Studies with laboratory rodents have opened the path to the understanding of UV-induced immune-depression, carcinogenesis, photo-damage and photo-aging. The results of these studies have enabled other scientists to investigate the same phenomena in human organs such as the skin and the eye. UV radiation damages hair, as well. The present knowledge in these fields is summarized in some of the chapters of this monograph.Mass phenomenon in Europe with the generalization of summer vacations which were a consequence of social reforms introducing the concept of "paid vacations". This created a need for protection and opened a market for sunscreens. This monograph is concerned with sun protection as a whole and is not just "another book on sunscreens". Nonetheless, in these days of general concern, it is important to learn about the efficiency of sunscreens. Several authors discuss how to reduce the number of impinging photons and explain why sunscreens seem to offer less protection than expected. Guidelines are given on how to use sunscreens in everyday life, which are expressed rigorously though clearly, for access to the common reader.Our knowledge on the relationship between sun and humans is at the early stages of development. Industrial and commercial activities are concerned by the development of this knowledge, and rules have been and will be promulgated to guarantee efficacy and safety of sun-products. It is hoped that this monograph will be of interest to the scholar, the layman and the legislator.
 

เนื้อหา

bone health cancer prevention mental health and well being
11
a clinical overview
39
Chapter 4 The effects of sunlight on the skin of Asians
69
Chapter 5 Effects of solar radiation on the human immune system
91
photoaging of the skin its clinical appearance and underlying mechanisms
115
Chapter 7 The epidemiology of solar radiation and skin cancer
131
Chapter 8 Hazards of sunlight exposure to the eye
155
a microscopy study
175
Chapter 21 p53 protein and the response of human skin to UV
407
Chapter 22 Effects of solar radiation on detoxification mechanisms in the skin
419
Chapter 23 Eye protection from sunlight damage
437
Chapter 24 Artificial protection against solar radiation fabrics
457
Chapter 25 Self tanning
487
Chapter 26 Photochemical and photophysical properties of sunscreens
495
use and misuse
521
practical applications
535

Chapter 10 UV damage to nucleic acid components
207
reaction mechanisms cytotoxic consequences and defense strategies
231
Chapter 12 Photooxidation of proteins and its consequences
251
Chapter 13 Erythema a link between UVinduced DNA damage cell death and clinical effects?
277
Chapter 14 UV radiation mutations and oncogenic pathways in skin cancer
287
Chapter 15 Modulation of gene expression by solar ultraviolet radiation
303
cultured cells as a model system
321
lessons from the fluoroquinolones
337
Chapter 18 UVinduced pigmentation in human skin
357
Chapter 19 Nucleotide excision repair of UVradiation induced photolesions in human cells
377
the role of heat shock proteins
393
Chapter 29 Protection against solar radiation protective properties of antioxidants
561
Chapter 30 Systemic photoprotection Dietary intervention and therapy
573
Chapter 31 Enhancement of repair of UV damage in humans
593
Chapter 32 Boosting the immune system
613
Chapter 33 Skin pigmentation enhancers
637
Chapter 34 Metabolic effects of solar radiation and enhancers of energy metabolism
677
safety and regulatory issues
691
Chapter 36 Solar radiation at the Earths surface
705
Index
739
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